Hydrothermal Extraction and Micronization of Polysaccharides from Ganoderma lucidum in a One-Step Process
نویسندگان
چکیده
منابع مشابه
Hydrothermal Extraction and Micronization of Polysaccharides from Ganoderma lucidum in a One- Step Process
Ganoderma lucidum (G. lucidum) is a mushroom-forming white rot fungus that contains a wide variety of bioactive components (glucans). In this study, G. lucidum was utilized for the extraction of polysaccharides by hot compressed water at a temperature of 160 o C and a pressure of 4.0 MPa using a semi-batch system. Under these conditions, thermal softening of G. lucidum occurred, allowing the re...
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Medicinal mushroom Ganoderma lucidum has been used in East Asia for centuries in order to prevent and treat a variety of diseases such as hepatitis, immunological disorders and cancers. In fact, this fungus contains a vast source of polysaccharides, proteins and secondary metabolites with anti-tumor and immuno-modulatory properties. Up to now, a variety of drug metabolites extracted from G. luc...
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AIM To investigate the antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide (GLPP). METHODS Antitumor effect of GLPP was observed in tumor-bearing mice in vivo. At the same time, the effects of GLPP on proliferation of tumor cells and human umbilical cord vascular endothelial cell (HUVEC) were detected by MTT assay in vitro. Subsequently, spleen lymphocytes prol...
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Our previous studies demonstrated that Ganoderma lucidum polysaccharides (Gl-PS) exhibit potent immunomodulating effects. Immunomodulation plays an important role in hematopoiesis. To investigate the possible mechanism by which Gl-PS promote myelopoiesis during myelosuppression induced by cyclophosphamide, mice were injected intraperitoneally (i.p.) once daily with 2.5 mg/kg of Gl-PS for 10 day...
متن کاملOptimization of alkaline extraction of polysaccharides from Ganoderma lucidum and their effect on immune function in mice.
Response surface methodology was employed to optimize the conditions for alkaline extraction of polysaccharides from Ganoderma lucidum. The results indicated that the optimum conditions were an extraction temperature of 60.1 degrees C, an extraction time of 77.3 min, a sodium hydroxide (NaOH) concentration of 5.1% and a substrate/liquid ratio of 1:21.4. Immunological assays results have shown t...
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ژورنال
عنوان ژورنال: BioResources
سال: 2012
ISSN: 1930-2126
DOI: 10.15376/biores.8.1.461-471